Step	Pathway	KO	FRH46_2	FRH46_3	FRH46_4	FRH46_5	FRH46_6	FRH47_2	FRH47_3	FRH47_4	FRH47_5	FRH47_6	FRH48_2	FRH48_3	FRH48_4	FRH48_5	FRH48_6	FRH49_3	FRH49_4	FRH49_5	FRH49_6	FRH50_3	FRH50_4	FRH50_5	FRH50_6	FRH51_2	FRH51_3	FRH51_4	FRH51_5	FRH51_6	FRH52_3	FRH52_4	FRH52_5	FRH52_6	FRH53_3	FRH53_4	FRH53_5	FRH53_6	FRH54_2	FRH54_4	FRH54_5	FRH54_6	FRH55_2	FRH55_4	FRH55_5	FRH55_6	FRH56_2	FRH56_3	FRH56_4	FRH56_5	FRH56_6	FRH57_3	FRH57_4	FRH57_5	FRH57_6
Sulfate to APS	Assimilatory sulfate reduction	K00958	7	1	1	3	4	0	2	4	5	4	2	0	1	0	4	6	2	3	3	2	2	14	8	0	1	1	2	2	2	1	4	7	5	5	8	12	0	5	0	0	1	2	2	4	1	0	2	0	0	8	4	7	7
Sulfate to APS	Assimilatory sulfate reduction	K00955	6	3	5	6	15	3	21	34	35	34	1	1	3	5	25	13	12	17	17	15	33	51	36	4	3	3	4	4	5	8	8	7	5	12	29	21	0	5	1	3	2	2	7	23	3	0	11	0	3	11	14	27	35
APS to PAPS	Assimilatory sulfate reduction	K00955	6	3	5	6	15	3	21	34	35	34	1	1	3	5	25	13	12	17	17	15	33	51	36	4	3	3	4	4	5	8	8	7	5	12	29	21	0	5	1	3	2	2	7	23	3	0	11	0	3	11	14	27	35
PAPS to Sulfite	Assimilatory sulfate reduction	K00390	15	5	6	10	17	4	29	46	48	42	6	4	5	12	38	18	13	20	19	20	43	73	56	5	7	7	10	10	9	10	16	18	12	22	45	34	0	11	1	3	3	4	9	36	5	0	13	0	3	22	21	41	51
Sulfite to Sulfide	Assimilatory sulfate reduction	K00380	5	1	3	0	4	2	7	10	10	7	0	0	1	5	7	4	4	4	3	3	8	13	10	0	2	3	3	3	3	1	6	5	3	4	7	3	0	2	0	1	0	0	2	12	4	0	0	0	2	2	4	5	8
Sulfite to Sulfide	Assimilatory sulfate reduction	K00392	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1	0	0	0	0	0	0	0	0	0	1	0	0	0	3	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Sulfate to APS	Dissimilatory sulfute reduction and oxidation	K00958	7	1	1	4	4	0	2	4	5	4	2	0	1	0	4	4	2	3	3	2	2	14	8	0	1	1	2	2	2	1	3	7	5	5	8	12	0	5	0	0	1	2	2	4	1	0	2	0	0	8	4	7	7
Sulfite to Sulfide	Dissimilatory sulfute reduction and oxidation	K11180	1	0	1	1	3	0	2	2	2	3	0	0	0	0	0	4	3	6	5	0	0	4	3	1	1	0	1	1	0	0	0	0	2	1	2	2	0	1	0	0	0	0	1	0	0	0	0	0	0	0	0	0	1
Thiosulfate to Sulfate	Sox System	K17222	6	1	2	3	6	1	2	6	7	6	1	0	1	1	2	4	3	5	4	2	4	13	8	0	1	1	2	3	4	6	4	6	3	3	7	8	0	5	0	1	1	1	3	9	2	0	3	0	2	7	3	4	6
Thiosulfate to Sulfate	Sox System	K17223	5	1	1	3	4	0	2	5	6	4	1	0	1	1	2	4	2	4	3	2	4	12	7	0	1	1	2	3	4	6	3	5	3	3	7	8	0	5	0	0	1	1	3	7	2	0	3	0	2	7	3	4	6
Thiosulfate to Sulfate	Sox System	K17226	8	2	4	6	11	1	7	16	17	16	1	0	1	2	6	12	11	15	13	10	13	23	20	2	2	4	6	6	5	6	6	6	6	6	16	15	0	7	0	1	1	1	5	20	3	0	5	0	2	10	7	10	13
Thiosulfate to Sulfate	Sox System	K17227	7	1	3	3	7	1	3	7	8	3	1	0	1	1	3	7	6	10	8	4	8	17	12	0	1	1	3	3	5	6	5	6	4	4	8	9	0	5	0	1	1	1	4	13	2	0	3	0	2	7	3	4	7
Thiosulfate to Sulfate	Sox System	K17224	5	2	1	3	4	0	2	5	6	3	1	0	1	1	2	4	2	4	3	1	4	10	7	0	1	1	2	3	4	6	3	5	3	3	7	8	0	5	0	0	1	1	3	8	2	0	3	0	1	6	3	4	6
SoxYZ-S-SH to Sulfate	Sox System	K17225	3	1	2	3	3	0	2	3	4	2	1	0	1	1	2	3	2	4	2	5	8	12	8	0	1	1	2	3	5	6	4	5	2	4	6	5	0	4	0	0	1	1	3	11	2	0	3	0	2	7	3	4	6
SoxYZ-S-SH to Sulfate	Sox System	K17224	5	2	1	3	4	0	2	5	6	3	1	0	1	1	2	4	2	4	3	1	4	10	7	0	1	1	2	3	4	6	3	5	3	3	7	8	0	5	0	0	1	1	3	8	2	0	3	0	1	6	3	4	6