Step	Pathway	KO	FRH46_2	FRH46_3	FRH46_4	FRH46_5	FRH46_6	FRH47_2	FRH47_3	FRH47_4	FRH47_5	FRH47_6	FRH48_2	FRH48_3	FRH48_4	FRH48_5	FRH48_6	FRH49_3	FRH49_4	FRH49_5	FRH49_6	FRH50_3	FRH50_4	FRH50_5	FRH50_6	FRH51_2	FRH51_3	FRH51_4	FRH51_5	FRH51_6	FRH52_3	FRH52_4	FRH52_5	FRH52_6	FRH53_3	FRH53_4	FRH53_5	FRH53_6	FRH54_2	FRH54_4	FRH54_5	FRH54_6	FRH55_2	FRH55_4	FRH55_5	FRH55_6	FRH56_2	FRH56_3	FRH56_4	FRH56_5	FRH56_6	FRH57_3	FRH57_4	FRH57_5	FRH57_6
Nitrogen to Ammonia	Nfixation	K02586	3	1	2	1	6	0	3	4	4	6	0	0	0	0	0	5	6	10	8	2	1	6	6	2	1	1	2	2	2	0	0	0	2	1	5	1	0	0	0	0	0	0	1	0	3	0	0	0	0	0	0	0	2
Nitrate to Nitrite	Nitrification	K00370	0	0	0	0	1	0	0	0	0	0	0	1	1	0	0	0	0	0	0	0	0	0	1	0	0	0	1	0	1	5	0	1	0	1	0	0	0	1	1	1	0	0	2	0	0	0	2	0	1	0	0	0	1
Nitrate to Nitrite	Denitrification	K00370	0	0	0	0	1	0	0	0	0	0	0	1	1	0	0	0	0	0	0	0	0	0	1	0	0	0	1	0	1	5	0	1	0	1	0	0	0	1	0	1	0	0	2	0	0	0	2	0	1	0	0	0	1
Nitrate to Nitrite	Denitrification	K02567	0	0	0	1	1	0	4	6	5	4	1	0	0	1	2	1	0	1	1	1	3	4	2	0	0	0	0	0	2	5	4	3	1	5	7	1	0	3	0	0	0	3	4	6	1	0	2	0	0	5	5	5	7
Nitrite to Nitric Oxide	Denitrification	K00368	0	0	0	1	0	0	3	3	3	2	0	2	1	1	2	0	0	1	1	1	2	5	3	0	0	0	1	0	2	0	2	0	0	5	6	3	0	1	1	1	0	1	3	5	1	0	2	0	1	3	4	4	6
Nitrite to Nitric Oxide	Denitrification	K15864	0	0	0	0	1	0	0	1	1	0	1	0	0	0	0	0	0	0	0	0	1	1	1	0	0	0	0	0	1	5	2	3	0	0	1	0	0	1	0	0	0	0	1	2	0	0	1	0	0	1	1	1	3
Nitric Oxide to Nitrous oxide	Denitrification	K04561	0	0	0	1	1	0	3	5	4	2	1	1	1	1	2	0	0	1	1	1	3	5	3	0	0	0	1	0	2	5	4	5	0	5	7	3	0	3	1	1	0	1	5	10	1	0	5	0	1	5	5	5	7
Nitrous oxide to Nitrogen	Denitrification	K00376	0	0	0	1	1	0	3	5	4	2	1	0	0	1	2	0	0	1	1	1	3	4	2	0	0	0	0	0	2	5	4	4	0	4	6	2	0	4	0	0	0	0	4	8	0	0	3	0	0	5	5	5	6
Nitrite to Nitric Oxide	Anammox	K00368	0	0	0	1	0	0	3	3	3	2	0	2	1	1	2	0	0	1	1	1	2	5	3	0	0	0	1	0	2	0	2	0	0	5	6	3	0	1	1	1	0	1	3	5	1	0	2	0	1	3	4	4	6
Nitrite to Nitric Oxide	Anammox	K15864	0	0	0	0	1	0	0	1	1	0	1	0	0	0	0	0	0	0	0	0	1	1	1	0	0	0	0	0	1	5	2	3	0	0	1	0	0	1	0	0	0	0	1	2	0	0	1	0	0	1	1	1	3
Nitrate to Nitrite	Assimilatory nitrate reduction	K00372	6	2	4	1	8	3	10	17	18	17	0	0	2	5	15	4	5	7	6	7	19	30	18	0	2	3	4	4	6	1	9	6	6	12	19	10	0	5	0	1	0	3	4	22	5	0	4	0	2	13	11	16	20
Nitrite to Ammonia	Assimilatory nitrate reduction	K00366	1	0	1	0	2	1	0	1	1	3	0	0	0	0	0	0	1	1	1	0	0	3	1	0	0	0	0	0	2	0	1	1	0	0	0	0	0	0	0	1	0	0	1	3	2	0	0	0	2	0	0	0	0
Nitrate to NItrite	Dissimilatory nitrate reduction	K00370	0	0	0	0	1	0	0	0	0	0	0	1	1	0	0	0	0	0	0	0	0	0	1	0	0	0	1	0	1	5	0	1	0	1	0	0	0	1	0	1	0	0	2	0	0	0	2	0	1	0	0	0	1
Nitrate to NItrite	Dissimilatory nitrate reduction	K02567	0	0	0	1	1	0	4	6	5	4	1	0	0	11	2	1	0	1	1	1	3	4	2	0	0	0	0	0	2	5	5	3	1	5	7	1	0	3	0	0	0	1	4	7	1	0	2	0	0	5	5	5	7
Nitrite to Ammonia	Dissimilatory nitrate reduction	K00362	6	2	4	3	8	3	11	18	19	17	0	0	2	5	15	5	5	7	6	9	21	31	19	0	3	3	4	4	6	1	9	6	6	13	20	10	0	5	0	1	0	3	4	23	6	0	4	0	2	13	11	16	20