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Finite element results (archive): low RyR density, with mitochondria
datasetposted on 07.05.2019 by David Ladd
Datasets usually provide raw data for analysis. This raw data often comes in spreadsheet form, but can be any collection of data, on which analysis can be performed.
Results from a reaction-diffusion finite element model of calcium signalling in a rat ventricular cardiomyocyte. Solved for the first 30 ms of the calcium transient in an 8 sarcomere section.
Calcium is released from RyR clusters with a minimum 1um spacing between them (50 clusters per z-disk). Regions representing mitochondria are excluded to produce barriers to diffusion in the intracellular space.
To view the results of the calcium and fluorescence-bound calcium fields, visualisation of the results in the 'vtk' folder with ParaView is recommended. All field data is available in OpenCMISS exnode / exelem formats in the 'output' folder. Note this model was run on 4 parallel processes.