Altered Outer Retinal Structure, Electrophysiology and Visual Perception in Parkinson’s Disease Study Dataset
This dataset is from a pilot cross-sectional study where we considered whether clinically implementable measures targeting outer retinal function and structure can differentiate Parkinson's disease (PD) from healthy ageing in a similar manner to previously reported inner retinal outcomes. As a proof of principle, we also considered whether outer retinal biomarkers are sensitive to patients’ standard intraday levodopa (L-DOPA) dosing regimen. Sixteen people with PD and 21 age-matched controls (aged 41-85 years) participated in this study. Centre-surround perceptual contrast suppression, macular visual field sensitivity, colour discrimination, light-adapted electroretinography and optical coherence tomography were tested. Electroretinography and optical coherence tomography were conducted twice during the visit: before and after a midday L-DOPA dose for PD participants, or repeated after approximately two hours for control participants.
Multimodal retinal imaging provides "insight" into cerebrovascular ageing
Australian Research CouncilFind out more...
Melbourne Neuroscience Institute Interdisciplinary Seed Fund
Melbourne Research Fellowship
Melbourne Neuroscience Institute Fellowship
Melbourne School of Health Sciences Seed Funding
John Landman PhD Scholarship
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