Ladd, David Finite element results (archive): low RyR density, with mitochondria Results from a reaction-diffusion finite element model of calcium signalling in a rat ventricular cardiomyocyte. Solved for the first 30 ms of the calcium transient in an 8 sarcomere section.<div><br></div><div>Calcium is released from RyR clusters with a minimum 1um spacing between them (50 clusters per z-disk). Regions representing mitochondria are excluded to produce barriers to diffusion in the intracellular space.</div><div><br></div><div>To view the results of the calcium and fluorescence-bound calcium fields, visualisation of the results in the 'vtk' folder with ParaView is recommended. All field data is available in OpenCMISS exnode / exelem formats in the 'output' folder. Note this model was run on 4 parallel processes. </div> calcium signalling;cardiomyocyte;reaction-diffusion;Finite element modelling;excitation-contraction coupling;Cell Biology;Cardiology;Computational Biology 2019-05-07
    https://melbourne.figshare.com/articles/dataset/Finite_element_results_archive_low_RyR_density_with_mitochondria/8067404
10.26188/5cd1275a2d54d