%0 DATA
%A David, Ladd
%D 2019
%T Finite element results (archive): low RyR density, with mitochondria
%U https://melbourne.figshare.com/articles/Finite_element_results_archive_low_RyR_density_with_mitochondria/8067404
%R 10.26188/5cd1275a2d54d
%2 https://melbourne.figshare.com/ndownloader/files/15033773
%K calcium signalling
%K cardiomyocyte
%K reaction-diffusion
%K Finite element modelling
%K excitation-contraction coupling
%X Results from a reaction-diffusion finite element model of calcium signalling in a rat ventricular cardiomyocyte. Solved for the first 30 ms of the calcium transient in an 8 sarcomere section.

Calcium is released from RyR clusters with a minimum 1um spacing between them (50 clusters per z-disk). Regions representing mitochondria are excluded to produce barriers to diffusion in the intracellular space.

To view the results of the calcium and fluorescence-bound calcium fields, visualisation of the results in the 'vtk' folder with ParaView is recommended. All field data is available in OpenCMISS exnode / exelem formats in the 'output' folder. Note this model was run on 4 parallel processes.